The artist has donated the complete sum of his £25,000 Mercury Prize cash to the MVT, which functions to protect the Britain's independent concert spaces.
He was awarded the cheque on 16 October as his new release People Watching was chosen as the best record of the previous year.
The musician has decided to donate the funds to the trust, in appreciation of the essential function local spots played in his early career.
"As an artist wouldn't be doing this success if it weren't for all the gigs I performed around the area, and further afield, when I was just getting going," remarked Fender. "These locations are renowned, but they are in difficulty."
From early 2023 onward, at least 150 of these locations have ceased operations – about 16 percent of the total UK scene.
In the last year, well-known musicians like the band Pulp, the group Coldplay, Katy Perry and Sheeran have all supported the MVT in its initiatives to keep the scene afloat, by including a minor surcharge to their admission fees, which supports independent venues.
He also took part, collecting more than £100,000 on his recent tour to support 38 small stages across Britain.
These funds assisted venues that were dealing with possible closure due to issues arising from water damage, fire incidents and family tragedies, as well as permit problems, legal disputes and sound issues.
Some locations obtained financial assistance in upgrading amenities and technical equipment that directly benefitted musicians and audiences.
"The idea that revenue from concerts in major spaces backs the local stages, where it begins for performers like me, is just logical," Sam Fender has said.
Fender is far from the only musician to contribute his honor funds to good deeds.
When the band earned the trophy in the mid-90s for their album Different Class, lead singer the singer declared that the group would contribute their prize money to the non-profit War Child.
In 2002, rapper and singer Ms Dynamite split her bounty among several organizations, like the NSPCC and a Sickle Cell organization.
"Additionally, I gave a thousand pounds to Highgate Newtown, to their gymnastics class, because I did gymnastics when I was younger and they required new equipment," Ms Dynamite shared with outlets.
Two years ago, the band contributed their winnings to the local youth club that nurtured their group, as well as other grassroots music organisations.
And winners that year M People donated their award to a multiple sclerosis charity after a acquaintance was diagnosed the condition.
"Winning was sufficient," remarked singer the singer. "The prize was the extra but we could do without the extra, because we had the cake. So our winning touched somebody else's life."
Last week, the trust shared it had rescued two small stages in that region, by bringing them into local control.
One venue in that area and the other in the city were acquired under the public acquisition scheme, which is funded by the arts council and music fans who acquire "stakes" in the buildings.
